CoQ10

之前看到報導Q10 對心血管很好

因為媽媽有嚴重的心臟肥大的買Q10 給爸媽

Costco 的q10 是自己進口的所以比其他地方便宜很多…..

以下為wiki找到的資料

在美國是銷售量第三高的保健食品哦

http://en.wikipedia.org/wiki/Coenzyme_Q10

Supplementation benefits

Coenzyme Q10 is the 3rd most sold dietary ingredient in the United States after omega-3 and multivitamins.

According to the Mayo Clinic^[36] "CoQ10 has been used, recommended, or studied for numerous conditions, but remains controversial as a treatment in many areas." Further clinical results are needed to determine whether supplementation with coenzyme Q₁₀ is beneficial for healthy people.

[edit]Mitochondrial disorders

Supplementation of coenzyme Q₁₀ is a treatment for some of the very rare and serious mitochondrial disorders and other metabolic disorders, where patients are not capable of producing enough coenzyme Q₁₀ because of their disorder.^[37] Coenzyme Q₁₀ is then prescribed by a physician.^[38]

[edit]Heart failure

There is some clinical evidence^[39] that supplementation with coenzyme Q₁₀ is beneficial in treatment of patients with congestive heart failure. However, The American College of Cardiology published in 2005 an expert consensus document concluding that the value of coenzyme Q₁₀ in cardiovascular disease has not been clearly established.^[40] The Mayo clinic says that there is not enough scientific evidence to recommend for or against the use of CoQ₁₀ in patients with coronary heart disease.^[36]

[edit]Migraine headaches

Supplementation of coenzyme Q₁₀ has been found to have a beneficial effect on the condition of some sufferers of migraine headaches. So far, three studies have been done, of which two were small, did not have a placebo group, were not randomized, and were open-label,^[41] and one was a double-blind, randomized, placebo-controlled trial, which found statistically significant results despite its small sample size of 42 patients.^[42] Dosages were 150 to 300 mg/day.

[edit]Cancer

CoQ₁₀ is also being investigated as a treatment for cancer, and as relief from cancer treatment side-effects.^[43]

[edit]Cardiac arrest

Another recent study shows a survival benefit after cardiac arrest if coenzyme Q₁₀ is administered in addition to commencing active cooling of the body to 90–93 degrees Fahrenheit (32–34 degrees Celsius).^[44]

[edit]Blood pressure

There are several reports concerning the effect of CoQ₁₀ on blood pressure in human studies.^[45] In a recent (2007) meta-analysis of the clinical trials of CoQ₁₀for hypertension, a research group led by Professor Frank Rosenfeldt (Director, Cardiac Surgical Research Unit, Alfred Hospital, Melbourne, Australia) reviewed all published trials of coenzyme Q₁₀ for hypertension, and assessed overall efficacy, consistency of therapeutic action, and side-effect incidence. Meta-analysis was performed in 12 clinical trials (362 patients) comprising three randomized controlled trials, one crossover study, and eight open-label studies. The research group concluded that coenzyme Q₁₀ has the potential in hypertensive patients to lower systolic blood pressure by up to 17 mm Hg and diastolic blood pressure by up to 10 mm Hg without significant side-effects.^[46]

[edit]Periodontal disease

Studies have shown that diseased gum tissue is deficient in CoQ₁₀ compared to healthy gum tissue.^[47],[48] Human clinical trials have suggested a link between oral administration of CoQ10 and improved gingival health,^[49] immune response in gum tissues,^[50] and a reversal of the diseased gum conditions.^[51]In addition to oral supplementation, topical application of CoQ10 on gum tissues has been shown to improve periodontitis and gingivitis conditions.^[52]

[edit]Lifespan

One study demonstrated that low dosages of coenzyme Q₁₀ reduce oxidation and DNA double-strand breaks, and a combination of a diet rich inpolyunsaturated fatty acids and coenzyme Q₁₀ supplementation leads to a longer lifespan in rats.^[53] Coles and Harris demonstrated an extension in the lifespan of rats when they were given coenzyme Q₁₀ supplementation.^[54] But multiple studies have since found no increase in lifespan or decrease in aging in mice and rats supplemented with coenzyme Q₁₀. ^{[55] [56] [57] [58]} Another study demonstrated that coenzyme Q₁₀ extends the lifespan of C. elegans(nematode).^[59]

[edit]Radiation injury

A 2002 study reported that, in rat experiments, coenzyme Q₁₀ taken as dietary supplement reduced radiation damage to the animals' blood.^[60]

[edit]Parkinson's disease

A 2002 study in 80 Parkinson's disease patients found 1200mg/day reduced the progression by 44%.^{[61] [62]}

[edit]See also